Saw palmetto is commercially available alone and in combination products such as capsules, gel capsules and tablets. There are over 100 commercial products containing saw palmetto as a single ingredient or as a combination product. Among the chemicals present in saw palmetto are steroids (beta-sitosterol), fixed oils, essential oils and flavonoids.
Well why saw palmetto? For starters there are no known health risks or side effects are known concerning the proper administration of designated therapeutic dosages. Stomach problems after consumption have been reported rarely. Patients with hormone-dependent cancers should observe caution and talk to your doctor about the use of saw palmetto, due to its antiestrogenic, estrogenic and anti – androgenic effects. The use of Saw Palmetto with pregnancy and lactation is not recommended because of possible hormonal effects.
Saw palmetto has been used in herbal medicine for a number of reasons, such as a diuretic and an expectorant for bronchial and catarrhal problems. The renewed interest is mainly their effects on the male reproductive system, and various properties have been attributed to it, for example, is said to be useful in the treatment of problems associated with a nonmalignant enlargement of the prostate and impotence, but is also used as an aphrodisiac in men. In women, it has sometimes been claimed to be effective for enlargement breast.
There have been numerous human and animal research. In Germany, the drug is compatible with the relief of micturition (urination) in certain stages of the enlargement nonmalignant prostate but does not seem to reduce the enlargement of the real. It was also noted that only fat-soluble components of the drug is active, so A tea with water soluble components is not effective. Part of the scientific explanation of drug action might be to inhibit a large percentage of the activity of prostatic enzyme 5-a-reductase, involved in the enlargement of the prostate. Due to the reported hormone-like (anti-androgens and estrogens) the drug activities may interfere with existing hormone therapy (oral contraceptives and hormone replacement). Its use during pregnancy and lactation should be avoided. Indeed, any use of the drug should be discussed with a medical consultant.
A study in rats, we evaluated the effects of saw palmetto and Cernitin (another natural product) and finasteride on prostate growth. In castrated rats receiving testosterone, the three treatments significantly reduced the size of the prostate compared with rats (castrated + testosterone) who received no treatment. Although finasteride produced the greatest effect on prostate size, not statistical difference was observed between any of the three treatments. Anti-inflammatory effects of saw palmetto has also been hypothesized to improve symptoms of BPH (6). An acid, lipophilic palmetto (Talso ®) has proven to prevent the formation of inflammatory prostaglandins which produce and leukotrienes.
Saw Palmetto in a dose of 160 mg or placebo three times daily was administered to 35 elderly men and prostate tissue was collected. The Researchers found that some components of the extract of saw palmetto inhibits nuclear estrogen receptors in the prostate of patients with patients with BPH. Clinically, Permixon ® 160 mg twice daily was superior to placebo in a double-blind trial in 110 men. A statistically significant benefit compared placebo was observed in nocturia, flow rate, residual after the evacuation, self-rating, number of doctors, and dysuria. Compared baseline with both placebo and saw palmetto were beneficial in improving nocturia, but only saw palmetto improved flow rate and then residual evacuation compared to baseline. Headache was the only adverse effect. A comparison study doubleblind Proscar ® (finasteride, a 5a-reductaseinhibitor recipe), 5 mg daily, with Permixon, 160 mg twice daily for 6 months. Both finasteride and improvement of saw palmetto International Prostate Symptom Score and quality of life compared to baseline, no statistical difference between the two treatments.
Another randomized, double-blind, placebo-controlled of saw palmetto for the treatment of urinary tract symptoms has also proved useful in such conditions. These researchers studied 85 men, randomized to receive saw palmetto or placebo for 6 months. The effectiveness was monitored using the I-PSS, a questionnaire on sexual function and flow rate urinal. The results of these studies demonstrated that the symptom score decreased I-PSS (ie, improved) 16.7 to 12.3 in subjects who received the palm American dwarf, whereas the symptom score decreased from 15.8 to 13.6 in the placebo group.
In addition, there were no differences in either score of sexual function questionnaire and peak urinary flow between saw palmetto and placebo groups. This study demonstrated that saw palmetto administration during 6 months resulted in an improvement in symptoms associated with BPH, but not sexual function or peak flow rate.
In addition, the Commission German E lists saw palmetto as an approved herb. The berry is the only part of the plant approved for use. Approved uses include urination problems associated with BPH stages I and II and urination problems associated with prostate adenoma. This assessment is based on reasonable evidence of safety and efficacy. Saw palmetto is considered a dietary supplement by the Food and Drug Administration (FDA). Saw palmetto was previously included in the National Formulary (NF) and the States Pharmacopeia U.S., but was abolished in 1950 and 1916, respectively. Saw palmetto has been removed because no active ingredient could be found to account for their use. Saw palmetto American was again included in the federation as an official monograph in 1998.
If you are seeking a natural solution for prostate problems bladder, saw palmetto is worth a look. Get medical advice from your family doctor is always a good idea to ensure that the resource can be adapted to their specific needs.
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