how are steroids different from lipids

by admin on September 10, 2006

Prednizone-the correct spelling is "prednisoneÂ" – is a commonly used drug with oral glucocorticoids.

The adrenal glands manufacture a natural form of glucocorticoids. Glucocorticoids are responsible for many functions in the body, including maintaining blood pressure, appropriate use sugar, protein, fat and metabolism, stress response, and many other tasks.

Glucocorticoids produced by the body referred significance of endogenous steroids to body of the person makes of these steroids.

When steroids are taken from the outside, either orally, intramuscular or intravenous injection, referred to exogenous steroids. Use of oral glucocorticoids or intravenously can reduce the ability of the glands themselves adrenal of the person to continue to produce glucocorticoids.

Without the ability to increase steroid production in the face of stressors such as injury, infection, and surgery, the patient may go into shock.

The potential for increased adrenal gland is suppressed dose a "outsidee" steroids exceeds the average daily production equivalent of the adrenal glands that is 5.0-7.5 mg of prednisone, treatment continues for more than a few weeks or months, the doses are listed at the end of the day or in divided doses, or long-acting preparations are used corticosteroids.

Patients requiring high doses of prednisone (more than 20 milligrams a day) for periods of time often develop side effects.

Taking steroid alternative in a day (every other day) schedule reduces the possibility of adrenal insufficiency, but not completely eliminated.

Other side effects include:

 • Increased risk of bacterial or opportunistic infections like fungal, tuberculosis, Pneumocystis carinii

 • High blood sugar

 • Changes in fat distribution that leads to moon face, buffalo hump

 • High blood lipids

 • Aggravation of hypertension

 • Electrolyte abnormalities as the blood potassium

 • Fluid retention leading to edema

 • Easy bruisibility

 • Increased body hair

 • Increased sweating

 • Purple stretch marks

 • Impaired wound healing

 • Glaucoma

 • Cataracts

 • Muscle wasting

 • Severe stomach ulcers

 • Pancreatitis

• Acceleration of a hardening of the arteries

 • The osteonecrosis (bone death)

 • psychiatric disorders

 • Insomnia

 • intestinal perforation

 • Masking infection

The use of prednisone for different diseases like arthritis is necessary to evaluate the potential benefits against risks. These benefits and risks must be discussed with your rheumatologist.

Mr.Ford’s Anatomy & Physiology: Lesson 02:09 part 2 Lipids


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